Expand What You Can Measure.
Advanced nanoparticle reagents for mass cytometry, spectral flow cytometry, and magnetic cell separation.
Core Quantum Technologies develops polymer-encapsulated nanoparticles engineered to expand detection capabilities, simplify cell workflows, and enable researchers to interrogate more biology.
Polymer Encapsulation
Stability & Biocompatibility
High Payload
Multiple metals or fluorophores per particle
Conjugatable Surface
for antibodies and ligands
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Mass Cytometry In development
Expand the measurable mass range.
Highly loaded metal nanoparticles designed to introduce new detection channels and expand high-dimensional mass cytometry panels without disrupting your existing backbone workflow.
Compatible with mass cytometry and mass imaging workflows.
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Spectral Flow Cytometry
Expand your panel.
Drop-in fluorescent reagents with narrow emission profiles spanning 420–700 nm, designed to expand your panel without disrupting your existing SSM.
Compatible with flow cytometry and fluorescence imaging.
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Magnetic Cell Separation
Separate. Detect. Analyze.
Magnetic and dual magnetic-fluorescent nanoparticles enable efficient cell enrichment with streamlined downstream analysis.
Applications include yeast display, immune cell isolation and rare cell enrichment.
One Platform. Multiple Payloads. New Capabilities.
Our polymer encapsulation technology enables diverse nanoparticle designs for a range of applications.
Fluorescent
Spectral Flow Cytometry
Fluorescence Imaging
Magnetic
Cell Separation
Magnetic + Fluorescent
Separation +
Direct Analysis
High Payload
More signal from every particle.
Stable
Protected payloads for reliable performance.
Conjugatable
Easily attach antibodies and ligands.
Versatile
One platform across instruments and workflows.
Expanding Mass Cytometry In development
Go Beyond Traditional Detection Channels
Mass cytometry enables highly multiplexed single-cell analysis, but available metal channels constrain how much biology can be measured simultaneously.
Core Quantum is developing a new class of highly loaded metal nanoparticle reagents designed to expand the measurable mass range and increase the number of markers that can be incorporated into mass cytometry panels.
New Mass Channels
Access masses beyond conventional reagent offerings.
High Metal Payload
Polymer-encapsulated particles carry multiple metal atoms per nanoparticle.
Antibody Conjugated
Designed for familiar antibody-based cellular workflows.
Panel Expansion
Add new markers while preserving valuable existing detection channels.
[NEEDS CONTENT: performance figure — source data required]
The mockup shows a CD8 signal comparison here. No chart, fold-change or caption is published until CQT supplies the underlying data and approves the claim.
Proven Across Cell Analysis Workflows
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Spectral Flow Cytometry
Narrow-emission fluorescent nanoparticles provide additional options for complex spectral panels.
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Magnetic Cell Separation
Magnetic nanoparticles enable targeted enrichment and depletion of cell populations.
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Yeast Display & Antibody Discovery
Dual magnetic-fluorescent MagDots enable magnetic enrichment followed by direct fluorescent analysis, simplifying antibody discovery workflows.
“Core Quantum’s expertise was instrumental in establishing our lab’s workflow. Their custom MagDot conjugations for our detection and enrichment antibodies worked seamlessly with our spectral cytometer to analyze Th17 cells bound to Nanovials. Without the high-quality service and innovative MagDots, our Th17 enrichment protocol would not have been possible. Thanks to the dual fluorescent and magnetic properties of the MagDots, we quickly validated our findings and are now uncovering new biology for Th17 cells that we can identify and isolate by protein expression. Core Quantum’s support has been invaluable in advancing our research.”
Dequina Nicholas, PhD, Assistant Professor, University of California Irvine, Molecular Biology and Biochemistry Department
What Could You Measure With Our Nanoparticles?
Whether you’re expanding a mass cytometry panel, building a spectral flow assay, or simplifying a cell separation workflow, our scientists can help determine how Core Quantum’s nanoparticle platform can support your research.